2014年6月10日星期二

growth retardation and other diseases.

JINGWAH

times dispatch (reporter Zhang Xiaoge) yesterday, Tsinghua University announced: the research group of Professor Yan Ning of the school of medicine in the world for the first time, the crystal structure of human sources of glucose transporter GLUT1, reveal the pathogenic mechanism of its working mechanism and related diseases, in the capture of human major diseases, cancer, diabetes and so on the road of exploration made a very important step. Future, the human is expected to "starve" cancer cells.

British "natural" magazine yesterday to Ban Ki Moon formally published the results. According to introduction, glucose is the diversity of life on earth is the most important, the most basic energy source, but also the human brain and Cheap Rams Jerseys nervous system the main energy substances. According to estimates, average daily consumption of about 120 grams of glucose, glucose consumption accounted for more than half of the Cheap Seahawks Jerseys total. The Cheap Broncos Jerseys first step in glucose metabolism is to enter the cell, Cheap Redskins Jerseys but the hydrophilic glucose, soluble in water, and the cell membrane is hydrophobic layer of oil, therefore, glucose itself cannot cross the cell membrane into the cell function, must rely on the transporter "transport machine" to complete the. Glucose transporter proteins embedded in the membrane, as opened a door in the membrane hydrophobic, can be from the extracellular glucose Cheap Jaguars Jerseys transport into cells.

Yan Ning professor said, glucose transporter GLUT1 exists in almost every cell in the human body, is the most important glucose transporter in brain, nervous system, muscles and other tissues and organs, is extremely important to maintain the body's normal physiological function. This transporter function deletion will cause death, partial loss of function can lead to brain atrophy, mental retardation, growth retardation and other diseases.

at the same time, the transporter also plays an important role in the cancer cells in The new supersedes the old. Cancer cells need to consume excess glucose to maintain its growth amplification, transporter GLUT1 in cells was significantly excessive often means the carcinogenesis.

"so, as we can study, results and the working mechanism of GLUT1, is possible through the regulation of glucose transport it realize manual intervention." Professor Yan Ning said, this can increase the glucose supply to normal cells, to the treatment of related diseases, but also by blocking the glucose supply to "starve" cancer cells.

(original title: the human is expected to "starve" cancer cell)

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